Reinventing Aseptic Fill-Finish

A New Era in Pharmaceutical Packaging


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TopFill is more than a technological
upgrade - it's a paradigm shift in pharmaceutical packaging. It offers a safer experience for patients, a sustainable path for the planet, and a scalable solution for manufacturers ready to meet the demands of tomorrow.

Yves Steffen, CEO Inductio

Developed through a strategic partnership between Dec Group and Inductio, the innovative TopFill Aseptic Filling Platform is now proudly unveiled. In the rapidly evolving world of pharmaceutical manufacturing, TopFill is setting a new benchmark for aseptic fill-finish operations. Built on the pillars of innovation, sustainability, and future-ready packaging, this system reimagines how drug products are processed, packaged, and delivered - bringing efficiency, safety, and environmental responsibility to the forefront.

Innovation that transforms

TopFill introduces Inductio's patented vial and closure system that arrives pre-assembled in its closed form and pre-sterilized , streamlining aseptic processing from start to finish. The vial closure ensures secure post-fill closure and enables rapid changeovers, ideal for both clinical and commercial production. 

The modular and scalable design integrates inline decontamination and rapid processing, while remaining fully compliant with EU GMP Annex 1 standards. A levitating transport system - frictionless and particle-free - enhances cleanliness and customization. Fully automated processes simplify training and reduce manufacturing complexity.

Sustainability at its core

TopFill's PFAS-free primary packaging underscores sustainability by design. By consolidating the supply chain into a single component, it significantly cuts CO2 emissions. The system also minimizes energy consumption, waste, and overall line footprint - supporting a low-impact, future-ready manufacturing system.

Packaging for the future

Designed for compatibility with Ready-To-Use (RTU) tub/nest configurations, TopFill's patented tamper-evident caps preserve product integrity across the supply chain. Quick format changes, secure handling, and reduced waste make it ideal for navigating complex regulatory environments with agility and confidence.

Key Benefits

  • Ultra-compact design: requires significantly less floor space compared to traditional filling lines at equivalent production

  • Lower CAPEX/OPEX: Smaller equipment and integrated vial systems reduce infrastructure, installation, and maintenance costs

  • Shorter delivery time: Streamlined manufacturing and modular design enable faster deployment and installation

  • Faster time to market: Pre-validated vials and machine components eliminate lengthy qualification processes, accelerating production readiness

  • Turnkey solution: Minimizes integration complexity and allows for rapid scale-up or replication across multiple sites

  • Regulatory compliance

  • Sustainable by design